Short Communication: Reassessing the Origin of the HIV-1 CRF02_AG Lineages Circulating in Brazil.
Identifieur interne : 000271 ( Main/Exploration ); précédent : 000270; suivant : 000272Short Communication: Reassessing the Origin of the HIV-1 CRF02_AG Lineages Circulating in Brazil.
Auteurs : Edson Delatorre [Brésil] ; Carlos A. Velasco-De-Castro [Brésil] ; José H. Pilotto [Brésil] ; José Carlos Couto-Fernandez [Brésil] ; Gonzalo Bello [Brésil] ; Mariza G. Morgado [Brésil]Source :
- AIDS research and human retroviruses [ 1931-8405 ] ; 2015.
Descripteurs français
- KwdFr :
- Adulte, Afrique (épidémiologie), Analyse de regroupements, Biologie informatique, Brésil (épidémiologie), Femelle, Grossesse, Génotype, Humains, Infections à VIH (transmission), Infections à VIH (virologie), Infections à VIH (épidémiologie), Mâle, Phylogéographie, VIH-1 (Virus de l'Immunodéficience Humaine de type 1) (), VIH-1 (Virus de l'Immunodéficience Humaine de type 1) (génétique), VIH-1 (Virus de l'Immunodéficience Humaine de type 1) (isolement et purification), Épidémiologie moléculaire.
- MESH :
- génétique : VIH-1 (Virus de l'Immunodéficience Humaine de type 1).
- isolement et purification : VIH-1 (Virus de l'Immunodéficience Humaine de type 1).
- virologie : Infections à VIH.
- épidémiologie : Afrique, Brésil, Infections à VIH.
- Adulte, Analyse de regroupements, Biologie informatique, Femelle, Grossesse, Génotype, Humains, Mâle, Phylogéographie, VIH-1 (Virus de l'Immunodéficience Humaine de type 1), Épidémiologie moléculaire.
- Wicri :
- geographic : Brésil.
English descriptors
- KwdEn :
- Adult, Africa (epidemiology), Brazil (epidemiology), Cluster Analysis, Computational Biology, Female, Genotype, HIV Infections (epidemiology), HIV Infections (transmission), HIV Infections (virology), HIV-1 (classification), HIV-1 (genetics), HIV-1 (isolation & purification), Humans, Male, Molecular Epidemiology, Phylogeography, Pregnancy.
- MESH :
- geographic , epidemiology : Africa, Brazil.
- classification : HIV-1.
- epidemiology : HIV Infections.
- genetics : HIV-1.
- isolation & purification : HIV-1.
- transmission : HIV Infections.
- virology : HIV Infections.
- Adult, Cluster Analysis, Computational Biology, Female, Genotype, Humans, Male, Molecular Epidemiology, Phylogeography, Pregnancy.
Abstract
HIV-1 CRF02_AG is responsible for at least 8% of the HIV-1 infections worldwide and is distributed mainly in West Africa. CRF02_AG has recently been reported in countries where it is not native, including Brazil. In a previous study including 10 CRF02_AG Brazilian samples, we found at least four independent introductions and two autochthonous transmission networks of this clade in Brazil. As more CRF02_AG samples have been identified in Brazil, we performed a new phylogeographic analysis using a larger dataset than before. A total of 20 Brazilian (18 from Rio de Janeiro and two from São Paulo) and 1,485 African HIV-1 CRF02_AG pol sequences were analyzed using maximum likelihood (ML). The ML tree showed that the Brazilian sequences were distributed in five different lineages. The Bayesian phylogeographic analysis of the Brazilian and their most closely related African sequences (n = 212) placed the origin of all Brazilian lineages in West Africa, probably Ghana, Senegal, and Nigeria. Two monophyletic clades were identified, comprising only sequences from Rio de Janeiro, and their date of origin was estimated at around 1985 (95% highest posterior density: 1979-1992). These results support the existence of at least five independent introductions of the CRF02_AG lineage from West Africa into Brazil and further indicate that at least two of these lineages have been locally disseminated in the Rio de Janeiro state over the past 30 years.
DOI: 10.1089/aid.2015.0183
PubMed: 26353079
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000408
- to stream PubMed, to step Curation: 000408
- to stream PubMed, to step Checkpoint: 000408
- to stream Ncbi, to step Merge: 000881
- to stream Ncbi, to step Curation: 000881
- to stream Ncbi, to step Checkpoint: 000881
- to stream Main, to step Merge: 000271
- to stream Main, to step Curation: 000271
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Short Communication: Reassessing the Origin of the HIV-1 CRF02_AG Lineages Circulating in Brazil.</title><author><name sortKey="Delatorre, Edson" sort="Delatorre, Edson" uniqKey="Delatorre E" first="Edson" last="Delatorre">Edson Delatorre</name><affiliation wicri:level="3"><nlm:affiliation>1 Laboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz-FIOCRUZ , Rio de Janeiro, Brazil .</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>1 Laboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz-FIOCRUZ , Rio de Janeiro</wicri:regionArea><placeName><settlement type="city">Rio de Janeiro</settlement><region type="state">État de Rio de Janeiro</region></placeName></affiliation></author><author><name sortKey="Velasco De Castro, Carlos A" sort="Velasco De Castro, Carlos A" uniqKey="Velasco De Castro C" first="Carlos A" last="Velasco-De-Castro">Carlos A. Velasco-De-Castro</name><affiliation wicri:level="3"><nlm:affiliation>2 Laboratório de Virologia, Departamento de Patologia Clínica, Instituto Nacional de Saúde da Mulher , da Criança e do Adolescente Fernandes Figueira-FIOCRUZ, Rio de Janeiro, Brazil .</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>2 Laboratório de Virologia, Departamento de Patologia Clínica, Instituto Nacional de Saúde da Mulher , da Criança e do Adolescente Fernandes Figueira-FIOCRUZ, Rio de Janeiro</wicri:regionArea><placeName><settlement type="city">Rio de Janeiro</settlement><region type="state">État de Rio de Janeiro</region></placeName></affiliation></author><author><name sortKey="Pilotto, Jose H" sort="Pilotto, Jose H" uniqKey="Pilotto J" first="José H" last="Pilotto">José H. Pilotto</name><affiliation wicri:level="3"><nlm:affiliation>1 Laboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz-FIOCRUZ , Rio de Janeiro, Brazil .</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>1 Laboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz-FIOCRUZ , Rio de Janeiro</wicri:regionArea><placeName><settlement type="city">Rio de Janeiro</settlement><region type="state">État de Rio de Janeiro</region></placeName></affiliation></author><author><name sortKey="Couto Fernandez, Jose Carlos" sort="Couto Fernandez, Jose Carlos" uniqKey="Couto Fernandez J" first="José Carlos" last="Couto-Fernandez">José Carlos Couto-Fernandez</name><affiliation wicri:level="3"><nlm:affiliation>1 Laboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz-FIOCRUZ , Rio de Janeiro, Brazil .</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>1 Laboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz-FIOCRUZ , Rio de Janeiro</wicri:regionArea><placeName><settlement type="city">Rio de Janeiro</settlement><region type="state">État de Rio de Janeiro</region></placeName></affiliation></author><author><name sortKey="Bello, Gonzalo" sort="Bello, Gonzalo" uniqKey="Bello G" first="Gonzalo" last="Bello">Gonzalo Bello</name><affiliation wicri:level="3"><nlm:affiliation>1 Laboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz-FIOCRUZ , Rio de Janeiro, Brazil .</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>1 Laboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz-FIOCRUZ , Rio de Janeiro</wicri:regionArea><placeName><settlement type="city">Rio de Janeiro</settlement><region type="state">État de Rio de Janeiro</region></placeName></affiliation></author><author><name sortKey="Morgado, Mariza G" sort="Morgado, Mariza G" uniqKey="Morgado M" first="Mariza G" last="Morgado">Mariza G. Morgado</name><affiliation wicri:level="3"><nlm:affiliation>1 Laboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz-FIOCRUZ , Rio de Janeiro, Brazil .</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>1 Laboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz-FIOCRUZ , Rio de Janeiro</wicri:regionArea><placeName><settlement type="city">Rio de Janeiro</settlement><region type="state">État de Rio de Janeiro</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:26353079</idno><idno type="pmid">26353079</idno><idno type="doi">10.1089/aid.2015.0183</idno><idno type="wicri:Area/PubMed/Corpus">000408</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000408</idno><idno type="wicri:Area/PubMed/Curation">000408</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000408</idno><idno type="wicri:Area/PubMed/Checkpoint">000408</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000408</idno><idno type="wicri:Area/Ncbi/Merge">000881</idno><idno type="wicri:Area/Ncbi/Curation">000881</idno><idno type="wicri:Area/Ncbi/Checkpoint">000881</idno><idno type="wicri:Area/Main/Merge">000271</idno><idno type="wicri:Area/Main/Curation">000271</idno><idno type="wicri:Area/Main/Exploration">000271</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Short Communication: Reassessing the Origin of the HIV-1 CRF02_AG Lineages Circulating in Brazil.</title><author><name sortKey="Delatorre, Edson" sort="Delatorre, Edson" uniqKey="Delatorre E" first="Edson" last="Delatorre">Edson Delatorre</name><affiliation wicri:level="3"><nlm:affiliation>1 Laboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz-FIOCRUZ , Rio de Janeiro, Brazil .</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>1 Laboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz-FIOCRUZ , Rio de Janeiro</wicri:regionArea><placeName><settlement type="city">Rio de Janeiro</settlement><region type="state">État de Rio de Janeiro</region></placeName></affiliation></author><author><name sortKey="Velasco De Castro, Carlos A" sort="Velasco De Castro, Carlos A" uniqKey="Velasco De Castro C" first="Carlos A" last="Velasco-De-Castro">Carlos A. Velasco-De-Castro</name><affiliation wicri:level="3"><nlm:affiliation>2 Laboratório de Virologia, Departamento de Patologia Clínica, Instituto Nacional de Saúde da Mulher , da Criança e do Adolescente Fernandes Figueira-FIOCRUZ, Rio de Janeiro, Brazil .</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>2 Laboratório de Virologia, Departamento de Patologia Clínica, Instituto Nacional de Saúde da Mulher , da Criança e do Adolescente Fernandes Figueira-FIOCRUZ, Rio de Janeiro</wicri:regionArea><placeName><settlement type="city">Rio de Janeiro</settlement><region type="state">État de Rio de Janeiro</region></placeName></affiliation></author><author><name sortKey="Pilotto, Jose H" sort="Pilotto, Jose H" uniqKey="Pilotto J" first="José H" last="Pilotto">José H. Pilotto</name><affiliation wicri:level="3"><nlm:affiliation>1 Laboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz-FIOCRUZ , Rio de Janeiro, Brazil .</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>1 Laboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz-FIOCRUZ , Rio de Janeiro</wicri:regionArea><placeName><settlement type="city">Rio de Janeiro</settlement><region type="state">État de Rio de Janeiro</region></placeName></affiliation></author><author><name sortKey="Couto Fernandez, Jose Carlos" sort="Couto Fernandez, Jose Carlos" uniqKey="Couto Fernandez J" first="José Carlos" last="Couto-Fernandez">José Carlos Couto-Fernandez</name><affiliation wicri:level="3"><nlm:affiliation>1 Laboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz-FIOCRUZ , Rio de Janeiro, Brazil .</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>1 Laboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz-FIOCRUZ , Rio de Janeiro</wicri:regionArea><placeName><settlement type="city">Rio de Janeiro</settlement><region type="state">État de Rio de Janeiro</region></placeName></affiliation></author><author><name sortKey="Bello, Gonzalo" sort="Bello, Gonzalo" uniqKey="Bello G" first="Gonzalo" last="Bello">Gonzalo Bello</name><affiliation wicri:level="3"><nlm:affiliation>1 Laboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz-FIOCRUZ , Rio de Janeiro, Brazil .</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>1 Laboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz-FIOCRUZ , Rio de Janeiro</wicri:regionArea><placeName><settlement type="city">Rio de Janeiro</settlement><region type="state">État de Rio de Janeiro</region></placeName></affiliation></author><author><name sortKey="Morgado, Mariza G" sort="Morgado, Mariza G" uniqKey="Morgado M" first="Mariza G" last="Morgado">Mariza G. Morgado</name><affiliation wicri:level="3"><nlm:affiliation>1 Laboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz-FIOCRUZ , Rio de Janeiro, Brazil .</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>1 Laboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz-FIOCRUZ , Rio de Janeiro</wicri:regionArea><placeName><settlement type="city">Rio de Janeiro</settlement><region type="state">État de Rio de Janeiro</region></placeName></affiliation></author></analytic><series><title level="j">AIDS research and human retroviruses</title><idno type="eISSN">1931-8405</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Africa (epidemiology)</term><term>Brazil (epidemiology)</term><term>Cluster Analysis</term><term>Computational Biology</term><term>Female</term><term>Genotype</term><term>HIV Infections (epidemiology)</term><term>HIV Infections (transmission)</term><term>HIV Infections (virology)</term><term>HIV-1 (classification)</term><term>HIV-1 (genetics)</term><term>HIV-1 (isolation & purification)</term><term>Humans</term><term>Male</term><term>Molecular Epidemiology</term><term>Phylogeography</term><term>Pregnancy</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Afrique (épidémiologie)</term><term>Analyse de regroupements</term><term>Biologie informatique</term><term>Brésil (épidémiologie)</term><term>Femelle</term><term>Grossesse</term><term>Génotype</term><term>Humains</term><term>Infections à VIH (transmission)</term><term>Infections à VIH (virologie)</term><term>Infections à VIH (épidémiologie)</term><term>Mâle</term><term>Phylogéographie</term><term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1) ()</term><term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1) (génétique)</term><term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1) (isolement et purification)</term><term>Épidémiologie moléculaire</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Africa</term><term>Brazil</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>HIV-1</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>HIV-1</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1)</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>HIV-1</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1)</term></keywords><keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Infections à VIH</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Afrique</term><term>Brésil</term><term>Infections à VIH</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Cluster Analysis</term><term>Computational Biology</term><term>Female</term><term>Genotype</term><term>Humans</term><term>Male</term><term>Molecular Epidemiology</term><term>Phylogeography</term><term>Pregnancy</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Analyse de regroupements</term><term>Biologie informatique</term><term>Femelle</term><term>Grossesse</term><term>Génotype</term><term>Humains</term><term>Mâle</term><term>Phylogéographie</term><term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1)</term><term>Épidémiologie moléculaire</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Brésil</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">HIV-1 CRF02_AG is responsible for at least 8% of the HIV-1 infections worldwide and is distributed mainly in West Africa. CRF02_AG has recently been reported in countries where it is not native, including Brazil. In a previous study including 10 CRF02_AG Brazilian samples, we found at least four independent introductions and two autochthonous transmission networks of this clade in Brazil. As more CRF02_AG samples have been identified in Brazil, we performed a new phylogeographic analysis using a larger dataset than before. A total of 20 Brazilian (18 from Rio de Janeiro and two from São Paulo) and 1,485 African HIV-1 CRF02_AG pol sequences were analyzed using maximum likelihood (ML). The ML tree showed that the Brazilian sequences were distributed in five different lineages. The Bayesian phylogeographic analysis of the Brazilian and their most closely related African sequences (n = 212) placed the origin of all Brazilian lineages in West Africa, probably Ghana, Senegal, and Nigeria. Two monophyletic clades were identified, comprising only sequences from Rio de Janeiro, and their date of origin was estimated at around 1985 (95% highest posterior density: 1979-1992). These results support the existence of at least five independent introductions of the CRF02_AG lineage from West Africa into Brazil and further indicate that at least two of these lineages have been locally disseminated in the Rio de Janeiro state over the past 30 years.</div></front></TEI><affiliations><list><country><li>Brésil</li></country><region><li>État de Rio de Janeiro</li></region><settlement><li>Rio de Janeiro</li></settlement></list><tree><country name="Brésil"><region name="État de Rio de Janeiro"><name sortKey="Delatorre, Edson" sort="Delatorre, Edson" uniqKey="Delatorre E" first="Edson" last="Delatorre">Edson Delatorre</name></region><name sortKey="Bello, Gonzalo" sort="Bello, Gonzalo" uniqKey="Bello G" first="Gonzalo" last="Bello">Gonzalo Bello</name><name sortKey="Couto Fernandez, Jose Carlos" sort="Couto Fernandez, Jose Carlos" uniqKey="Couto Fernandez J" first="José Carlos" last="Couto-Fernandez">José Carlos Couto-Fernandez</name><name sortKey="Morgado, Mariza G" sort="Morgado, Mariza G" uniqKey="Morgado M" first="Mariza G" last="Morgado">Mariza G. Morgado</name><name sortKey="Pilotto, Jose H" sort="Pilotto, Jose H" uniqKey="Pilotto J" first="José H" last="Pilotto">José H. Pilotto</name><name sortKey="Velasco De Castro, Carlos A" sort="Velasco De Castro, Carlos A" uniqKey="Velasco De Castro C" first="Carlos A" last="Velasco-De-Castro">Carlos A. Velasco-De-Castro</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/SidaGhanaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000271 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000271 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= SidaGhanaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:26353079
|texte= Short Communication: Reassessing the Origin of the HIV-1 CRF02_AG Lineages Circulating in Brazil.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:26353079" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a SidaGhanaV1
| This area was generated with Dilib version V0.6.31. |  |